Stem Cell Injections Using Amniotic Fluid As Regenerative Medicine

Soft tissue injuries and defects can now be treated with regenerative medicine using amniotic fluid.

Stem cell therapy has risen to the forefront of medical research in recent years. The majority of therapy is performed using a technique known as Platelet Rich Plasma, or PRP. This method involves drawing the patient’s blood and centrifuging it to collect the available cells in the blood draw. The concentrated blood is re-injected into the designated site for therapy after collection and processing. PRP therapy normally entails a series of injections, usually three, spaced out over a set period of time. You can learn more at QC Kinetix (Austin)

Although this therapy has had some success, it does have some disadvantages. The technique can only produce a fraction of the amount of stem cells that other injection substances can. Adult cells also don’t always have the ability to differentiate into all types of human tissue, including cartilage, muscle, tendon, and bone.

Each person’s body contains a certain number of stem cells when they are born. With around 1 in 10,000 cells, the stem cell level is at its highest at birth. This degree decreases as you get older. When a child reaches the age of adolescence, the number decreases to 1 in 100,000 cells. At the age of thirty, it drops to 1 in 250,000 cells. According to Caplan, A. Clinics in Plastic Surgery 1994, the risk is 1 in 400,000 at fifty years old and 1 in 2,000,000 at eighty years old.

Treatments dependent on amniotic fluid are the next step in regenerative medicine. Amniotic fluid not only includes a large number of stem cells, but it also contains a biological structure that contributes to the advantages. Proteins, growth factors, and multipotent stem cells found in amniotic fluid have been shown to be essential for foetal growth and development. Medical evidence shows that the existence of these cells enhances the body’s natural regenerative mechanism when filling soft tissue gaps, resulting in additional clinical benefits.

Amniotic fluid contains no foetal tissue, removing the ethical issues associated with embryonic cells and preserving the life of multipotent cells. These cells are still undifferentiated and can turn into cartilage, bone, or muscle cells. Embryonic cells have the ability to overproduce cells, resulting in tumours, while amniotic fluid stem cells do not.

According to current medical research, cytokines, growth factors, hyaluronic acids, and stem cells found in amniotic tissue and fluid promote tissue repair or modulate the local microenvironment by enhancing the body’s natural regenerative process, potentially allowing damaged tissue to regenerate.

Currently, therapies include tissue replacement or removal, such as surgery, or allowing the body to heal itself. In the case of a cartilage defect in the knee, the normal mechanism is for fibrocartilage to fill in the gap. This isn’t true cartilage, so it doesn’t have the same defensive properties. Using an amniotic fluid-based stem cell injection, real cartilage may theoretically fill the defect, preventing post-traumatic joint degeneration. Another example is a meniscal tear, for which the most common procedure is arthroscopic surgery with the tear removed. The meniscus is the knee’s shock absorber, and removing too much of it can cause premature arthritis. It would be preferable to encourage regeneration rather than elimination.

The multiple benefits seen with amniotic fluid’s ingredients may provide a key treatment choice for regenerative medicine, and there are several potent clinical treatment options with stem cells.